河北醫(yī)科大學(xué)導(dǎo)師：郭艷蘇 正文

[導(dǎo)師姓名]
郭艷蘇

[所屬院校]
河北醫(yī)科大學(xué)

[基本信息]
導(dǎo)師姓名：郭艷蘇
性別：女
人氣指數(shù)：782
所屬院校：河北醫(yī)科大學(xué)
所屬院系：
職稱：主任醫(yī)師
導(dǎo)師類型：
招生專業(yè)：神經(jīng)病學(xué)

[通訊方式]
辦公電話：66003712
電子郵件：gys188@163.com

[個(gè)人簡述]
郭艷蘇，女，河北醫(yī)科大學(xué)第二醫(yī)院神經(jīng)內(nèi)科，主任醫(yī)師，教授，碩士生導(dǎo)師。河北省醫(yī)學(xué)會(huì)神經(jīng)病學(xué)分會(huì)青年委員。2013.4-2015.3美國馬薩諸塞大學(xué)醫(yī)學(xué)院訪問學(xué)者。研究方向?yàn)樯窠?jīng)變性疾病及神經(jīng)病理。
先后主持國家自然科學(xué)基金1項(xiàng)、河北省自然科學(xué)基金1項(xiàng)、河北省科技廳重點(diǎn)基礎(chǔ)研究項(xiàng)目2項(xiàng)、河北省衛(wèi)生廳醫(yī)學(xué)科學(xué)研究重點(diǎn)課題6項(xiàng)。獲河北省科技進(jìn)步二等獎(jiǎng)2項(xiàng)、河北省科技進(jìn)步三等獎(jiǎng)1項(xiàng)。發(fā)表SCI論文38篇，著作1部。培養(yǎng)碩士研究生6名。被評(píng)為河北醫(yī)科大學(xué)中青年骨干教師，獲第七屆石家莊市青年科技獎(jiǎng)。

[科研工作]
1．Guo Y, Wang D, Qiao T, Yang C, Su Q, Gao G, Xu Z. A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord. Mol Neurobiol. 201653(5):3235-48. 2. An T, Shi P, Duan W, Zhang S, Yuan P, Li Z, Wu D, Xu Z, Li C, Guo Y*. Oxidative Stress and Autophagic Alteration in Brainstem of SOD1-G93A Mouse Model of ALS. Mol Neurobiol, 2014 49(3):1435-48. 3. Zhang K, Shi P, An T, Wang Q, Wang J, Li Z, Duan W, Li C, Guo Y*. Food restriction- induced autophagy modulates degradation of mutant SOD1 in an amyotrophic lateral sclerosis mouse model. Brain Res. 2013 1519: 112-9. 4. Guo Y, Zhang Y, Wen D, Duan W, An T, Shi P, Wang J, Li Z, Chen X, Li C. The modest impact of transcription factor Nrf2 on the course of disease in an ALS animal model. Lab Invest. 2013 93(7): 825-33. 5. Guo Y, Wang Q, Zhang K, An T, Shi P, Li Z, Duan W, Li C. HO-1 induction in motor cortex and intestinal dysfunction in TDP-43 A315T transgenic mice. Brain Res. 2012 1460: 88-95. 6. Guo Y, Zhang K, Wang Q, Li Z, Yin Y, Xu Q, Duan W, Li C. Neuroprotective effects of diallyl trisulfide in SOD1-G93A transgenic mouse model of amyotrophic lateral sclerosis. Brain Res. 2011 1374: 110-5. 7. Guo Y, Duan W, Li Z, Huang J, Yin Y, Zhang K, Wang Q, Zhang Z, Li C. Decreased GLT-1 and increased SOD1 and HO-1 expression in astrocytes contribute to lumbar spinal cord vulnerability of SOD1-G93A transgenic mice. FEBS Lett. 2010 584(8): 1615-22. 8. Guo Y, Li C, Wu D, Wu S, Yang C, Liu Y, Wu H, Li Z. Ultrastructural Diversity of Inclusions and Aggregations in the Lumbar Spinal Cord of SOD1-G93A Transgenic Mice. Brain Res, 2010 1353: 234-244. 9. Guo Y, Liu Y, Xu L, Wu D, Wu H, Li CY. Reduced Nrf2 and Phase II Enzymes Expression in Immune-mediated Spinal Cord Motor Neuron Injury. Neurol Res. 2010 32(5): 460-5.

[教育背景]
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河北醫(yī)科大學(xué)

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