陳蕓 ，博士
地址：南京市漢中路140號(hào)藥學(xué)院
郵編：210029
電話：025-86862764
E-mail： ychen@njmu.edu.cn
陳蕓，2000年獲南京大學(xué)化學(xué)學(xué)士學(xué)位，同年保送南京大學(xué)分析化學(xué)專業(yè)，2002年獲碩士學(xué)位。7月赴美國(guó)明尼蘇 達(dá)大學(xué)(University of Minnesota, UMN)攻讀博士學(xué)位，主要從事抗腫瘤藥物的分子作用機(jī)理研究。2006年12月獲生物分析化學(xué)博士學(xué)位。同年10月，赴美國(guó)Charles River實(shí)驗(yàn)室工作，主要研究方向是新藥的臨床藥代動(dòng)力學(xué)。2008年9月回國(guó)，進(jìn)入南京醫(yī)科大學(xué)工作，擔(dān)任藥學(xué)院臨床藥學(xué)專業(yè)教授。

研究興趣：
（1） 亞細(xì)胞藥代動(dòng)力學(xué)，（2）抗腫瘤藥物的分子作用機(jī)制，（3）臨床蛋白組學(xué)和基因組學(xué)。

主要發(fā)表論文如下：
? Chen, Y.; Qiao, S.; Wang, X.; Liu, Y., "An investigation into fragmentation of hEGF in triple quadrupole mass spectrometry and its quantitative application to human plasma". International Journal of Mass Spectrometry, 2010, 295： 7-12.
? Chen, Y.; Pei. J., “Factors influencing the association between CYP17 T34C polymorphism and the risk of breast cancer： meta-regression and subgroup analysis”. Breast Cancer Research and Treatment, 2010, 122, 471-81.
? Chen, Y.; Qiao, S.; Wang, C., “Fragmentation of Peptides with Intra-Chain Disulfide Bonds in Triple Quadrupole Mass Spectrometry and its Quantitative Application to Biological Samples.” International Journal of Mass Spectrometry, 2009, 288, 68-74
? Chen, Y.; Pei. J., “An Assessment of a TNF Polymorphic Marker for the Risk of HCV Infection： Meta-analysis and a New Clinical Study Design”. Infection, Genetics and Evolution, 2009, 9, 1356-63.
? Chen, Y.; Liu, Y.; Wang, C., “Utilization of Immonium Product Ions for the Determination of Peptide Drugs with Intra-loops in Biological Matrices”. Analytical Letters , 2009, 42, 3004-3017.
? Chen, Y.; Arriaga, E. A., “Individual Electrophoretic Mobilities of Liposomes and Acidic Organelles Displaying pH Gradients Across Their Membranes”. Langmuir, 2007, 23, 5584-90.
? Chen, Y.; Xiong, G.; Arriaga, E. A., “CE analysis of the acidic organelles of a single cell”. Electrophoresis, 2007, 28, 2406-15.
? Chen, Y.; Arriaga, E. A., “Individual Acidic Organelle pH Measurements by Capillary Electrophoresis”, Analytical Chemistry, 2006, 78, 820-826.
? Chen, Y.; Walsh, R. J.; Arriaga, E. A., “Individual Organelle Analysis for Selective Determination of the Doxorubicin Content of Acidic Organelles in Impure Subcellular Fractions”, Analytical Chemistry, 2005, 77, 2281-2287.
? Xiong, G.; Chen, Y.; Arriaga, E. A., “Measuring the Doxorubicin Content of Single Nuclei by Micellar Electrokinetic Capillary Chromatography with Laser-Induced Fluorescence Detection”, Analytical Chemistry, 2005, 77, 3488-3493.
? Liu, S; Chen. Y.; Chen. H., “Studies of Spectroscopy and Cyclic Voltammetry on a Zirconium Hexacyanoferrate Modified Electrode”. Journal of Electroanalytical Chemistry, 2001, 502, 197-203.
? Liu, S; Chen, Y.; Chen. H., “Electrochemical Studies on a Zirconium Hexacyanoferrate Modified Electrode and Utility for the Determination of Rubidium.” Electroanalysis, 2001, 14, 116-121.

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