寧波大學(xué)醫(yī)學(xué)院導(dǎo)師:葉孟
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寧波大學(xué)醫(yī)學(xué)院導(dǎo)師:葉孟 正文
[導(dǎo)師姓名]葉孟
[所屬院校]
寧波大學(xué)
[基本信息]
導(dǎo)師姓名:葉孟
性別:男
人氣指數(shù):2648
所屬院校:寧波大學(xué)
所屬院系:醫(yī)學(xué)院
職稱(chēng):主任醫(yī)師
導(dǎo)師類(lèi)型:
招生專(zhuān)業(yè):腫瘤學(xué)
研究領(lǐng)域:腫瘤內(nèi)科及腫瘤分子生物學(xué)
[通訊方式]
電子郵件:yemeng@nbu.edu.cn
[個(gè)人簡(jiǎn)述]
副教授,主任醫(yī)師,腫瘤學(xué)博士,碩士生導(dǎo)師,寧波大學(xué)醫(yī)學(xué)院附屬醫(yī)院副院長(zhǎng),腫瘤內(nèi)科主任,浙江省腫瘤防治聯(lián)盟副主席,浙江省免疫學(xué)會(huì)腫瘤免疫與生物治療專(zhuān)業(yè)委員會(huì)委員,浙江省細(xì)胞生物學(xué)會(huì)醫(yī)學(xué)細(xì)胞生物學(xué)專(zhuān)業(yè)委員會(huì)委員,浙江省抗癌協(xié)會(huì)腫瘤化療專(zhuān)業(yè)委員會(huì)常委,浙江省抗癌協(xié)會(huì)乳腺癌專(zhuān)業(yè)委員會(huì)常委,浙江省中西醫(yī)結(jié)合學(xué)會(huì)腫瘤專(zhuān)業(yè)委員會(huì)委員,寧波市康復(fù)醫(yī)學(xué)會(huì)副會(huì)長(zhǎng),寧波市中西醫(yī)結(jié)合學(xué)會(huì)副會(huì)長(zhǎng),寧波市中西醫(yī)結(jié)合學(xué)會(huì)腫瘤分會(huì)主任委員,寧波醫(yī)學(xué)會(huì)醫(yī)學(xué)教育分會(huì)秘書(shū),寧波醫(yī)學(xué)會(huì)腫瘤學(xué)分會(huì)委員,寧波市江北區(qū)黨外知識(shí)分子聯(lián)誼會(huì)副會(huì)長(zhǎng);寧波市優(yōu)秀中青年衛(wèi)生技術(shù)人才,寧波市“4321人才工程”人才,主持多項(xiàng)省市自然基金和博士基金,發(fā)表論文50余篇,3項(xiàng)主持課題獲浙江省教育廳科研成果三等獎(jiǎng)和浙江省醫(yī)藥衛(wèi)生進(jìn)步獎(jiǎng)三等獎(jiǎng),參編腫瘤學(xué)專(zhuān)著2本。
[科研工作]
1. Meng Ye#*, Tao Huang, Jinyun Li, Chongchang Zhou, Ping Yang, Chao Ni, Si Chen. Role of CDH13 promoter methylation in the carcinogenesis, progression, and prognosis of colorectal cancer: A systematic meta-analysis under PRISMA guidelines, Medicine (Baltimore),2017, 96(4):e5956
2. Meng Ye#*, Tao Huang, Ying Ying, Jinyun Li, Ping Yang, Chao Ni, Chongchang.Zhou, Si Chen. Detection of 14-3-3 sigma (σ) promoter methylation as a noninvasive biomarker using blood samples for breast cancer diagnosis, Oncotarget,2017,8(6):9230-42
3. Yongfu Shao#, Meng Ye*, Qier Li, Weiliang Sun, Guoliang Ye, Xinjun Zhang,Yunben Yang, Bingxiu Xiao, Junming Guo*, LncRNA-RMRP promotes carcinogenesis by acting as a miR-206 sponge and is used as a novel biomarker for gastric cancer, Oncotarget, 2016,7(25):37812-24
4. Tao Huang#, Jinyun Li#, Cheng Zhang, Qingxiao Hong, Danjie Jiang, Meng Ye*,Shiwei Duan*,Distinguishing Lung Adenocarcinoma from Lung Squamous Cell Carcinoma by Two Hypomethylated and Three Hypermethylated Genes: A Meta-Analysis, PLOS ONE, 2016,1(2):e0149088
5. Jinyun Li#,Chongchang Zhou,Haojie Zhou,Tianlian Bao,Tengjiao Gao,Xiangling Jiang,Meng Ye*,The association between methylated CDKN2A and cervical carcinogenesi and its diagnostic value in cervical cancer: a meta-analysis,Ther Clin Risk Manag,2016,2:1249-60
6. Tao Huang#,Xiaoying Chen,Qingxiao Hong,Zaichun Deng,Hongying Ma,Yanfei Xin,Yong Fang,Huadan Ye,Rujie Wang,Cheng Zhang,Meng Ye*,Shiwei Duan*,Meta-analyses of gene methylation and smoking behavior in a non-small cell lung cancer patients,Sci Rep,2015,5:8897
7. Yongfu Shao#, Meng Ye*, Xiaoming Jiang,Weiliang Sun,Xiaoyun Ding,Zhong Liu,Guoliang Ye, Xinjun Zhang, Bingxiu Xiao, Junming Guo*, Gastric juice long noncoding RNA used as a tumor marker for screening gastric cancer. Cancer. 2014,120(21):3320-8
8. YongfuShao#,HuilinChen,XiaomingJiang, ShengcanChen, PeifeiLi, MengYe*, QierLi, WeiliangSun, JunmingGuo*. Low expression of lncRNA-HMlincRNA717 in human gastric cancer and its clinical significances. Tumour Biol. 2014,35(10):9591-5
9. Shaomin Wang#,Meng Ye*,Shumin Ni. Multiple scalp metastases from colonic neuroendocrine carcinoma: case report and literature review. BMC Cancer. 2014,4: 305.
10. Cheng Chen#,Lingyan Wang,Qi Liao,Leiting Xu,Yi Huang,Cheng Zhang,Huadan Ye,Xuting Xu,Meng Ye*,Shiwei Duan*. Association Between Six Genetic Polymorphisms and Colorectal Cancer: A Meta-Analysis. Genet Test Mol Biomarkers. 201418(3):187-95.
11. Cheng Chen#, Lingyan Wang,Yi Huang,Cheng Zhang,Huadan Ye,Xuting Xu, Leiting Xu Meng Ye*, Shiwei Duan*. Association between TLR2, MTR, MTRR, XPC, TP73, TP53 genetic polymorphisms and gastric cancer: A meta-analysis. Clin Res Hepatol Gastroenterol. 201438(3):346-59.
12. Zaicun Deng#,Chao Cao,Yiming Yu,Hongyin Ma,Meng Ye*, Vascular ndothelial growth factor-634G/C and vascular endothelial growth factor-2578C/A polymorphisms and lung cancer risk: a case-control study and meta-analysis. Tumour Biol. 2014,35(3):1805-11
13. Yi Huang#, Xi Yu,Lingyan Wang,Shengjun Zhou,Jie Sun,Nan Feng,Sheng Nie,Jingmi Wu,Feng Gao,Bing Fei,Jianyong Wang,Zhiqing Lin,Xianru Li,Leiting Xu,Xiang Gao,Meng Ye*,Shiwei Duan*,Four genetic polymorphisms of lymphotoxin-alpha gene and cancer risk: a systematic review and meta-analysis,PLoS One,2013, 8(12):e82519
14. Cheng Chen#,Lingyan Wang,Qi Liao,Yi Huang,Huadan Ye,Fei Chen,Leiting Xu,Meng Ye*,Shiwei Duan*, Hypermethylation of EDNRB promoter contributes to the risk of colorectal cancer. Diagn Pathol. 2013,8(1):199
15. 王少敏,葉孟,倪曙民.結(jié)直腸癌組織Bcl-2蛋白表達(dá)及其臨床意義.等.中華腫瘤防治雜志,2013,20(4):285-287
浙江省腫瘤防治聯(lián)盟副主席,浙江省免疫學(xué)會(huì)腫瘤免疫與生物治療專(zhuān)業(yè)委員會(huì)委員,浙江省細(xì)胞生物學(xué)會(huì)醫(yī)學(xué)細(xì)胞生物學(xué)專(zhuān)業(yè)委員會(huì)委員,浙江省抗癌協(xié)會(huì)腫瘤化療專(zhuān)業(yè)委員會(huì)常委,浙江省抗癌協(xié)會(huì)乳腺癌專(zhuān)業(yè)委員會(huì)常委,浙江省中西醫(yī)結(jié)合學(xué)會(huì)腫瘤專(zhuān)業(yè)委員會(huì)委員,寧波市康復(fù)醫(yī)學(xué)會(huì)副會(huì)長(zhǎng),寧波市中西醫(yī)結(jié)合學(xué)會(huì)副會(huì)長(zhǎng),寧波市中西醫(yī)結(jié)合學(xué)會(huì)腫瘤分會(huì)主任委員,寧波醫(yī)學(xué)會(huì)醫(yī)學(xué)教育分會(huì)秘書(shū),寧波醫(yī)學(xué)會(huì)腫瘤學(xué)分會(huì)委員。
1. 榭寄生誘導(dǎo)結(jié)直腸癌細(xì)胞凋亡的NFKB信號(hào)轉(zhuǎn)導(dǎo)途徑的研究,寧波市博士基金,編號(hào)2005A610020,2005.1-2007.12
2. NFκB在多藥耐藥中的作用及其逆轉(zhuǎn)機(jī)制研究,寧波市醫(yī)藥衛(wèi)生基金,編號(hào)200529,2005.1-2007.12
3. 新的腫瘤抑制因子CYLD對(duì)腫瘤細(xì)胞的作用及其機(jī)制研究,浙江省自然基金,編號(hào)Y205604,2006.1-2008.12
4. β-Arrestins對(duì)腫瘤細(xì)胞的作用及相關(guān)分子機(jī)制研究,浙江省自然科學(xué)基金,編號(hào)2006002,2006.1-2008.12
5. BCL-3在結(jié)直腸癌發(fā)病及耐藥中的機(jī)理研究,寧波市社會(huì)發(fā)展項(xiàng)目,編號(hào)2011C50010,2011.1-2013.12
6. 浙江省重點(diǎn)科技創(chuàng)新團(tuán)隊(duì),編號(hào)2010R50046,2010.1-2014.12骨干成員
7. 寧波市消化系統(tǒng)惡性腫瘤診治新技術(shù)創(chuàng)新團(tuán)隊(duì),編號(hào)2011B82014 , 2012.2-2014.11 ,骨干成員
8. 胃癌新型標(biāo)志物的篩選及其臨床意義分析,寧波市科技局社發(fā)項(xiàng)目,編號(hào)2012C50005,2012.1-2014.12
9. 早期AD中LTD的受體及細(xì)胞內(nèi)信號(hào)機(jī)制研究,國(guó)家自然科學(xué)基金,編號(hào)81271209,2013.1-2013.12
10. 長(zhǎng)鏈非編碼RNA作為胃癌早期診斷標(biāo)志物的可行性研究,寧波市自然基金項(xiàng)目,編號(hào)2013A610206,2013.1-2015.12
11. MDFI啟動(dòng)子甲基化狀態(tài)在結(jié)直腸癌發(fā)生中的作用研究,寧波市自然基金項(xiàng)目,編號(hào)2014A610235,2014.5-2016.6
12. 國(guó)家級(jí)繼教項(xiàng)目《晚期腫瘤綜合治療及新進(jìn)展學(xué)習(xí)班》和省級(jí)繼教項(xiàng)目《惡性腫瘤姑息治療手段及應(yīng)用策略》
13. 寧波市“體內(nèi)植入材料的生物改性技術(shù)研究”創(chuàng)新團(tuán)隊(duì)項(xiàng)目2015B11050。Project of Scientific Innovation Team of Ningbo (2015B11050)。
14. 長(zhǎng)鏈非編碼 RNA RMRP 參與胃癌發(fā)生的分子機(jī)制研究及其臨床診斷價(jià)值分析,浙江省自然基金,編號(hào)LY16H160005,2016.1-2018.12
1. NFκB在多藥耐藥中的作用及其逆轉(zhuǎn)機(jī)制研究。浙江省教育廳,高校優(yōu)秀科研成果獎(jiǎng),三等獎(jiǎng), 2010年
2. NFκB在多藥耐藥中的作用及其逆轉(zhuǎn)機(jī)制研究。浙江省衛(wèi)生廳,醫(yī)藥衛(wèi)生進(jìn)步獎(jiǎng),三等獎(jiǎng), 2011年
3. 槲寄生誘導(dǎo)結(jié)直腸癌細(xì)胞凋亡的NFκB信號(hào)轉(zhuǎn)導(dǎo)途徑的研究。浙江省衛(wèi)生廳,醫(yī)藥衛(wèi)生進(jìn)步獎(jiǎng),三等獎(jiǎng), 2012年
4. 基于CTB的融合蛋白疫苗設(shè)計(jì)與抗I型糖尿病機(jī)制研究。寧波市人民政府,寧波市科學(xué)技術(shù)獎(jiǎng)三等獎(jiǎng),2012
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