華中農(nóng)業(yè)大學(xué)植物科技學(xué)院導(dǎo)師：廖玉才 正文

　　基本信息
　　姓名: 廖玉才 出生年月: 1954.4
　　性別: 男 碩/博導(dǎo)： 博導(dǎo)
　　民族: 漢 開(kāi)設(shè)課程： 分子生物學(xué)、遺傳學(xué)
　　職稱(chēng): 教授 研究方向： 1. 麥類(lèi)作物基因工程; 2.真菌毒素形成與控制分子機(jī)理; 3. 植物生物反應(yīng)器
　　學(xué)位: 自然科學(xué)博士

　　聯(lián)系方式
　　辦公電話(huà)：027-87283008
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　　個(gè)人簡(jiǎn)介
　　1983年獲華中農(nóng)業(yè)大學(xué)作物遺傳育種專(zhuān)業(yè)碩士學(xué)位，1989年荷蘭瓦赫寧根大學(xué)訪(fǎng)問(wèn)學(xué)者，1990-1994年德國(guó)亞琛大學(xué)分子遺傳研究所博士生，1994年獲德國(guó)亞琛大學(xué)分子生物學(xué)博士學(xué)位；1995-1996年為該所博士后，1997年回國(guó)，1998-2002年每年到德國(guó)亞琛大學(xué)分子生物技術(shù)所或英國(guó)約翰英納斯所開(kāi)展合作科研。主要從事麥類(lèi)作物抗赤霉病基因工程、鐮刀菌毒素形成與控制分子機(jī)理、重組抗體分離與表達(dá)分析、植物生物反應(yīng)器等研究，在《Nature Biotechnology》、《Journal of Proteome Research》、《Fungal Genetics and Biology》、《Phytopathology》、《Plant Cell Report》、《Mycological Research》、《遺傳學(xué)報(bào)》等國(guó)內(nèi)外專(zhuān)業(yè)期刊發(fā)表論文80多篇，已被引用700多次；獲省部級(jí)一等獎(jiǎng)1項(xiàng)、三等獎(jiǎng)1項(xiàng)，獲授權(quán)專(zhuān)利5項(xiàng)，申請(qǐng)專(zhuān)利7項(xiàng)，參編專(zhuān)著教材3部?，F(xiàn)為《農(nóng)業(yè)生物技術(shù)學(xué)報(bào)》和《麥類(lèi)作物學(xué)報(bào)》編委，《中國(guó)農(nóng)業(yè)科技導(dǎo)報(bào)》理事，湖北省新世紀(jì)高層次人才人選。在讀研究生30余人，外籍博士生4人。

　　科研項(xiàng)目
　　 1. 國(guó)家自然科學(xué)基金重點(diǎn)項(xiàng)目：基于抗體的植物真菌病害分子控制原理與技術(shù)研究
　　 2. 國(guó)家自然科學(xué)基金面上項(xiàng)目：抗體及其融合分子介導(dǎo)的抗赤霉病基因工程
　　 3. 國(guó)家自然科學(xué)基金面上項(xiàng)目：我國(guó)小麥赤霉病菌的遺傳多樣性及致病性和產(chǎn)毒性的分子基礎(chǔ)
　　 4.“十一”五國(guó)家科技支撐計(jì)劃：食品安全關(guān)鍵技術(shù)研究用
　　 5. 農(nóng)業(yè)部948項(xiàng)目：重組抗體及其融合分子介導(dǎo)的植物真菌病害控制技術(shù)引進(jìn)與應(yīng)用
　　 6. 教育部博士點(diǎn)基金：抗體基因工程及在作物赤霉病抗性改良中的應(yīng)用
　　 7. 科技部863項(xiàng)目：動(dòng)植物生物反應(yīng)器新技術(shù)研究
　　 8. 中-俄合作項(xiàng)目：植物抗體的表達(dá)及在植物抗病基因工程中的應(yīng)用
　　 9. 中-德合作項(xiàng)目：抗體融合蛋白防控植物和植物產(chǎn)品中黃曲霉菌及其毒素的研究
　　 10. 農(nóng)業(yè)部重大專(zhuān)項(xiàng)：抗赤霉病轉(zhuǎn)基因小麥新品系和新種質(zhì)創(chuàng)制
　　 11. 科技部973課題：有害物質(zhì)從飼料污染到畜禽產(chǎn)品殘留的傳遞規(guī)律研究
　　 12. 農(nóng)業(yè)部重點(diǎn)課題：轉(zhuǎn)基因小麥快速甄別及高通量檢測(cè)技術(shù)

　　發(fā)明專(zhuān)利及獲獎(jiǎng)情況
　　授權(quán)專(zhuān)利：
　　 1. Molecular pathogenicide mediated plant disease resistance. US Patent Number 6825325 B1, Issued on Nov. 30, 2004.
　　 2. Molecular pathogenicide mediated plant disease resistance. Indian Patent Number 192141, Issued on Aug. 17, 2004
　　 3. 鐮刀菌毒素的分子檢測(cè)方法及應(yīng)用. 專(zhuān)利號(hào)：ZL 200410009300.2; 授權(quán)日：2007.4.15
　　 4. 一種非抗生素篩選小麥轉(zhuǎn)基因植物的方法. 授權(quán)日：2010.10.19
　　 5. 一種農(nóng)桿菌介導(dǎo)的無(wú)抗生素篩選轉(zhuǎn)基因大麥植株的方法. ZL 2007 1 0051390.5; 授權(quán)日：2010.5.19

　　獲獎(jiǎng)：
　　 1. 小麥抗赤霉病性遺傳及體細(xì)胞抗病突變體的選育，國(guó)家教委科技進(jìn)步三等獎(jiǎng)，1995
　　 2. 食品及食品接觸材料有害殘留的高通量表征及安全性評(píng)價(jià)技術(shù)，國(guó)家質(zhì)量監(jiān)督檢驗(yàn)檢疫總局科技興檢獎(jiǎng)一等獎(jiǎng)，2010

　　發(fā)表的論文及著作
　　 1. Chen, F.-F., Zhang, J. T., Song, X.-S., Yang, J., Li H.-P., Tang, H., Liao, Y.-C*. Combined metabonomic and reverse transcription PCR analyses reveals systems metabolic changes of Fusarium graminearum induced by Tri5 gene deletion. Journal of Proteome Research, 2011, in press. (﹡通訊作者)
　　 2. Cheng, L., Li, H.-P., Qu, B., Huang, T., Tu, J.-X., Fu, T.-D., Liao, Y.-C*. Chloroplast transformation of rapeseed (Brassica napus) by particle bombardment of cotyledons. Plant Cell Reports, 2010, 29, 37:371-381.　
　　 3. Li, X., Zhang, J. B., Song, B., Li, H. P., Xu, H. Q., Qu, B., Dang, F. J., Liao, Y. C*. Resistance to Fusarium head blight and seedling blight in wheat is associated with activation of a cytochrome P450 gene. Phytopathology, 2010, 100:183-191.
　　 4. Xu, Y.-B., Li, H.-P., Zhang, J.-B., Song, B., Chen, F.-F., Duan, X.-J., Xu, H.-Q., Liao, Y.-C*. Disruption of the chitin synthase gene Chs1 from Fusarium asiaticum results in an altered structure of cell walls and reduced virulence. Fungal Genetics and Biology, 2010, 47: 205-215.
　　 5. Li, H.-P., Huang, T., Wang, C.-X., Liao, Y.-C*. An efficient regeneration system of barley cultivars from leaf base segments. Biologia Plantarum, 2009, 53: 733-736.
　　 6. Li, H.-P., Zhang, J.-B., Shi, R.-P., Huang, T., Fischer, R., Liao, Y.-C*. Engineering Fusarium head blight resistance in wheat by expression of a fusion protein containing a Fusarium-specific antibody and an antifungal peptide. Molecular Plant-Microbe Interaction, 2008, 21:1242-1248.
　　 7. Wang, J.-H., Li, H.-P., Qu, B., Zhang, J.-B., Huang, T., Chen, F.-F., Liao, Y.-C*. Development of a generic PCR detection of 3-acetyldeoxynivalenol-, 15-acetyldeoxynivalenol- and nivalenol-chemotypes of Fusarium graminearum clade. International Journal of Molecular Sciences, 2008, 9:2495-2504.
　　 8. Li, H.-P., Zhang, J.-B., Qu, B., Huang, T., Chen, F.-F., Xu, Y.-B., Wu, A.-B., P. Nicholson, Liao, Y.-C*. Phylogenetic species, mycotoxin chemotypes and geographical distribution of Fusarium asiaticum and F. graminearum on wheat spikes throughout China. Journal of Plant Pathology, 2008, 90:3-S3, 89.
　　 9. Hu, Z.-Q., Li, H.-P., Zhang, J.-B., Glinka, E., Liao, Y.-C*. Antibody-mediated prevention of Fusarium mycotoxins in the field. International Journal of Molecular Sciences, 2008, 9: 1915-1926.
　　 10. Qu, B., Li, H.-P., Zhang, J.-B., Xu, Y.-B., Huang, T., Wu, A.B., Zhao, C.-S., Carter, J., Nicholson, P., Liao, Y.-C*. Geographical distribution and genetic diversity of the Fusarium graminearum and F. asiaticum on wheat spikes throughout China. Plant Pathology, 2008, 57: 15-24.
　　 11. Qu, B., Li, H.-P., Zhang, J.-B., Huang, T., Carter, J., Liao, Y.-C*., P. Nicholson. Comparison of genetic diversity and pathogenicity of Fusarium head blight pathogens from China and Europe revealed by SSCP and seedling assays on wheat. Plant Pathology, 2008, 57:642-651.
　　 12. Zhang, J.-B., Li, H.-P., Dang, F.-J., Qu, B., Xu, Y.-B., Zhao, C.-S., Liao, Y.-C*. Determination of the trichothecene mycotoxin chemotypes and associated geographical distribution and phylogenetic species of the Fusarium graminearum clade from China. Mycological Research, 2007, 111:967-975.
　　 13. Liao, Y.-C*., Li, H.-P., Zhao, C.-S., Yao, M.-J., Zhang, J.-B., Liu, J.-L. Plantibodies: A novel strategy to create pathogen-resistant plants. Biotechnology and Genetic Engineering Reviews, 2006, 23:253-271.
　　 14. Li, H.-P., Wu, A.-B., Zhao, C.-S., Scholten, O., Loeffler, H., Liao, Y.-C*. Development of a generic PCR detection of deoxynivalenol- and nivalenol-chemotypes of Fusarium graminearum. FEMS Microbiology Letters, 2005, 243:505-511.
　　 15. Wu, A.-B.，Li., H.-P., Zhao, C.-S., Liao, Y.-C*. Comparative pathogenicity of Fusarium graminearum from China revealed by wheat coleoptile and floret inoculations. Mycopathologia, 2005, 160:75-83.
　　 16. Peschen, D., Li, H.-P., Fischer, R., Kreuzaler, F., Liao, Y.-C*. Fusion proteins comprising a Fusarium-specific antibody linked to anti-fungal peptides protect plants against fungal pathogens. Nature Biotechnology, 2004, 22:732-738.
　　 17. Li, H.-P., Fu, C.-Y., Fischer, R., Liao, Y.-C*. Cloning and characterization of a gene coding for a class I chitin synthase from Fusarium graminearum. Canadian Journal of Plant Pathology, 2003, 25:240-248.
　　 18. Li, H.-P., Fischer, R., Liao, Y.-C*. Molecular evidence for induction of phenylalanine ammonia lyase during Puccinia graminis infection and elicitation in wheat. Canadian Journal of Plant Pathology, 2001, 23:286-291.
　　 19. Zhang, M.-Y., Schillberg, S., Zimmermann, S., Liao, Y.-C., Breuer, G., Fischer, R. GST fusion proteins could cause false positive in screening phage-displayed antibody fragments. Journal of Virological Methods, 2001, 91:139-147.
　　 20. Fischer, R., Liao, Y.-C., Drossard, J. Affinity-purification of a TMV-specific recombinant full-size antibody from a transgenic tobacco suspension culture, Journal of Immunological Methods, 1999, 226:1-10.
　　 21. Fischer, R., Liao, Y.-C., Hoffmann, K., Schillberg, S., Emans, N. Molecular farming of recombinant antibodies in plants. Biological Chemistry, 1999, 380, 7/8:825-839.
　　 22. Spiegel, H., Schillberg, C., Sack, M., Holzem, A., Liao, Y.-C., Fischer, R. Accumulation of antibody fusion proteins in the cytoplasm and ER of plant cells. Plant Science, 1999, 146:1-9.
　　 23. Zimmermann, S., Schillberg, S., Liao, Y.-C., Fischer, R. Intracellular expression of TMV-specific single chain Fv fragments leads to improved virus resistance in Nicotiana tabacum. Molecular Breeding, 1998, 4: 369-379.
　　 24. Vaquero-Martin, C., Liao, Y.-C., Fischer, R. Use of non-radiactive probes to study protein-nucleic acids interactions by U.V.-crosslinking. Biotechniques, 1998, 24: 68-70.
　　　

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